Jansson M, 2014. Label-Free Cell-Based Assays and the Holistic Calorimetry Approach. American Laboratory Nov/Dec2014

The cell-based assay arena is slowly entering center stage due to the major and growing medical problems facing the world—both financial (i.e., drug development) and curative (i.e., antibiotic resistance). In a modern 3-D holistic format, the mature technique of calorimetry is the answer to some of these problems.

This article describes how and why measurement of the total metabolic response of a biological system is a valuable proposition and a true time- and cost-efficient complement to existing assays.

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