Why choose the calScreener™?

calScreener workflow

Test in difficult conditions

Opaque, viscous or solid media and any kind of cells or complex models

Accurate in-vivo prediction​

Mimic the natural environment of your sample

Direct metabolic readout

No proxies,

no additional reagents

Rapid detection

Detect metabolic activity as fast as 2 hours

Popular Applications

Sterility Testing

Sterility Testing for Cell and Gene Therapy

The calScreener label-free assay directly monitors the metabolic response in biological systems using bioactivity monitoring. We continuously develop new application areas with external collaborators and our applications team.



The fastest culture-based phenotypic detection method on the market.



Experience fast and phenotypic sterility testing that works on the most complex samples. Biocalorimetry lets you preserve your precious sample and release it to the patient as quickly as possible. The technology in our instrument, the calScreener™, enables small volumes so that you save most of your therapy for the patient. Testing couldn’t be simpler, add your sample into the calVial and leave it to incubate. The calScreener™ measures the metabolic output of your sample in real-time and will alert you at the earliest possible moment if contamination is detected. All you have to do is wait, but not for nearly as long as with other methods.


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How does it work?

The calScreener™ allows you to measure the total metabolic activity of your sample, in real-time, at your desired conditions and unlimited run-time that can be set from hours to months.


By directly measuring the heat produced as a result of metabolic processes in the sample, you get an energy output measured in μW, that provides new input not previously possible to see with traditional methods.

Explore applications

Antimicrobial Susceptibility Testing




Antimicrobials Development

Complex Models

Cancer Biology


We are using the calScreener to investigate the optimal treatment of in-vitro and in-vivo bacterial biofilm.
Thomas Bjarnsholt
Professor Thomas Bjarnsholt
The calScreener can be the solution to urgently needed customized treatments.
Christian giske
Professor Christian Giske

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