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Ultra-rapid sterility testing
The fastest detection of living organisms
Ultra-rapid? Yes.
Cell and gene therapies need to be available quickly, and they need to be safe. Yet traditional sterility tests’ long turnaround times and complex procedures can lead to long vein-to-vein times and high production and release costs.
By repurposing isothermal microcalorimetry to biological systems, our biocalorimetry is straightforward and remarkably fast, accurate and sensitive: Our calScreener+™ is dedicated specifically to rapid sterility testing. It is dramatically cutting today’s sterility testing time of 7-10 days, enabling release testing in <3 days – a cut of over 60%. Through continuous optimization, we will soon make it even faster.
Biofilm
Get the full picture - regardless of the substrate
Unlock the full potential of your biofilm studies with Symcel’s calScreener™.
Traditional methods often require compromise when defining your assays. The calScreener™ allows you to mirror in vivo-like conditions and can handle even the most complex of models or samples.
You can now explore the entire biofilm population, capturing all subpopulations and niches – even dormant ones deep within the biofilm – without disturbing or disrupting the biofilm structure or removing the cells.
Fast, sensitive and with no need for labels, stains or reagents, the calScreener™ is intuitive and easy to use.
Uncover the true complexity of biofilms and propel your research forward.
Welcome to next-generation biofilm research.
Clinical Research
Developing next-gen solutions for diagnosing complicated infections
We have a bold vision to transform in-vitro infection diagnostics by developing a one-stop-solution for detection, species ID and antimicrobial susceptibility testing (AST) – all using our biocalorimetry metabolic measurements matched with machine learning.
We’re changing the game. Get in touch and let’s see what we can achieve together.
Environmental and Microbiome
Beyond 'who is where?' research
Understanding interactions within microbiomes is a complex challenge, especially when those interactions are not directly tied to growth and cell numbers.
Interspecies synergy, competition, and other interactions within microbiomes can manifest in various ways beyond simple cell division, such as through changes in overall metabolic rates.
Unfortunately, most contemporary techniques for investigating microbiomes, such as plating and sequencing, focus primarily on identifying which species are present rather than understanding what they are actually doing.
Symcel’s calScreener™ changes the game.
Food
Microbiology
Beyond the traditional methods to a new standard
Detecting microbial contaminants in food ingredients and products is tricky, as they are often embedded deep within the product. Traditional techniques can be cumbersome, need extensive hands-on time and sample preparation, and produce false positives or negatives.
The Symcel calScreener™ detects contaminants deep inside even the most complex food products with minimal hands-on time.
There’s no extensive sample preparation, it differentiates between harmful foodborne pathogens and the normal flora naturally present in the product. And its speed is a game-changer, often delivering results within just hours instead of days.
Probiotics
Optimizing probiotic product development
Biocalorimetry, the science behind the calScreener™, is revolutionizing the way companies approach the development and quality of probiotics. Our technology simplifies the study of complex interactions, conserves valuable time and resources in screening, and ensures product safety and efficacy by identifying changes linked to antibiotic resistance.
The calScreener™ significantly simplifies media optimization for probiotic production, and delivers phenotypic readouts even in opaque and complex growth media. It measures the metabolism from single and multi-species cultures directly, as well as activity yield, setting a new standard in the field.
Its capabilities extend beyond traditional methods and offer researchers, manufacturers, and healthcare professionals a deeper understanding of probiotic functionality and new and exciting opportunities in research and product development.
Welcome to next-generation probiotic research