calScreener+™ Sterility
Dedicated to sterility testing
The calScreener+™ Sterility system is optimized for rapid sterility testing at two temperatures simultaneously to comply with regulatory guidelines. As such, it consists of two calScreener+™, one configured for measurement at 20-25 °C and one at 30-35 °C. Samples, loaded into single-use sterile glass vials with a volume of up to ~500 µL are placed into the calScreener+™. Each instrument can process up to 32 individual samples simultaneously, optimising throughput.
Each calScreener+™ unit comprises a multicalorimeter unit, a main thermostat, an external thermostat and the calView™ software for instrument control and data acquisition.
Additionally, the sterility testing system includes a Sample Handling Kit, complete with sample and loading plates, an automatic crimping tool, scissors, and a tweezer.
To ensure accurate measurements, each sample is paired with a calorimetric reference. The calorimeter reference should be completely inert with similar calorimetric properties as the sample. The system includes a full set (48) of these inert reference samples that also can be used as dummies for any unused sample positions.
The only consumables required for sterility testing are disposable sterile glass vials.
For laboratories needing regulatory compliance, the calScreener+™ offers a calView™ software module supporting 21 CFR Part 11 compliance and IQ/OQ protocols, ensuring adherence to FDA regulations.
calScreener+™ Biocalorimeter
Speed, simplicity, specificity, sensitivity
The calScreener+ ™ is the advanced, 2nd generation biocalorimeter from Symcel. It is a multichannel isothermal microcalorimeter specifically designed for measuring metabolic heat.
We have improved the devices to include a broader temperature range of 20°C to 42°C, superior signal stability, and reduced sensitivity to external environmental factors such as room temperature fluctuations.
These features ensure even more accurate and reproducible results, making the calScreener+ ™ ideal for applications that require the highest sensitivity.
calScreener™
CHANGING THE GAME
The calScreener™ label-free assay directly monitors the metabolic response in biological systems using bioactivity monitoring. We have developed the first isothermal microcalorimetry instrument designed for cell biology. High-precision cell metabolism monitoring based on a well-established scientific methodology.
The calScreener™ can be used to study the net effect of all cellular parameters at once and in the correct context, regardless of sample composition and morphology.
The calScreener™ is a true phenotype (functional) assay as compared to most other technologies that use parameter-based (genotype) testing.
