A new method published in JoVE highlights the work of the group of Professor Rolf Müller at the Helmholtz Centre for Infection Research. They have been using the calScreener to investigate how the metabolism of microorganisms changes when they are treated with novel antimicrobial compounds. The changes in metabolism can be used as a predictor or antimicrobial modes of action.
Additional Material
Dr. Jennifer Herrmann who coauthored the publication recently gave a webinar where she explained how they use microcalorimetry to measure metabolism and understand how novel antimicrobials are affecting different cellular processes.
To watch the webinar, register here:
Mode-of-action and resistance studies with novel antibacterial natural products
Dr. Jennifer Herrmann from the Helmholtz Centre for Infection Research talks about her research on antimicrobial resistance studies with novel antibacterial products.
.png)