Use of batch isothermal microcalorimetry for growth media optimization

This study presents the use of isothermal microcalorimetry for optimizing growth media in probiotic development. By continuously measuring metabolic heat flow, this approach allows real-time assessment of microbial activity under various media conditions, offering insights into growth rates and metabolic yield. The method provides an efficient and precise alternative to traditional biomass-focused techniques, facilitating the development of cost-effective, optimized media formulations.