In the ever-evolving landscape of microbial infection research, the need for accurate, clinically relevant in vitro models has never been more critical. Traditional methods, often reliant on...
Introduction Dental caries, commonly known as tooth decay or cavities, is a pervasive oral health problem affecting individuals of all ages. It poses significant challenges to public health due to...
Obesity is a huge global problem. According to the World Health Organization, worldwide obesity has nearly tripled since 1975. In a comprehensive global study in 2016, 1.9 billion adults were found...
Bacteria are able to perform a variety of stunts to confound common plate counting methods. They can adopt physiological states such as small colony variants and persisters which make them appear...
A new method published in JoVE highlights the work of the group of Professor Rolf Müller at the Helmholtz Centre for Infection Research. They have been using the calScreener to investigate how the...
There are not many methods that can claim to give a completely unique insight into your model system but isothermal microcalorimetry is one of them. Whether that is microbial biofilms or tissue...
Although Optical Density (OD) measurements have been traditionally applied to examine the growth of bacterial cultures, the technique of isothermal microcalorimetry is becoming widely used for its...
Direct measurements of metabolism can add a new dimension to research into biofilms. While there are different methods, microcalorimetry has a number of advantages that allow it to fit into various...